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Enhanced Th17 cell activity would explain the inflammation and immuno-pathology associated with leprosy reactions.
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Previous studies had shown that Th17 cells formed a third subset in leprosy and were seen in stable leprosy patients in the absence of Th1 and Th2 polarization[ 27 ].
J Clin Immunol 34 : —
Description: They were compared with complementary clinical groups of BT or LL respectively where the subjects were freshly diagnosed, untreated and without clinical evidence or previous history of reactions.